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Revelation of additional osteoblast differentiation indicators, such as cell stiffness, can improve identification and collection of starting cell populations, with applications to mesenchymal stem cell therapies and stem cell-based tissue engineering.
Moreover, expression of MUC17, junction marker (E-Cadherin), and alkaline phosphatase, as differentiation indicators of the epithelial cells, was significantly higher and earlier in the cell-laden structure compared to that in the control.
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It is presented in later strategies of neuronal progression and is classified as a differentiation indicator for neurogenesis, which may serve as a neuronal determination gene.
This study illustrates the value of incorporating information on regional adaptation and morphological differentiation as indicators of evolutionary divergence when studying phylogeographic breaks, in addition to the more commonly applied approach of investigating correlations between phylogeographic patterns and oceanographic features.
This inconsistency suggests that the varietal taxonomy is a poor indicator of genetic differentiation.> -wrap-foot> Above diagonal: pairwise genetic differentiation index (F ST ).
Interestingly, this tumour had sarcomatoid differentiation, an indicator of more aggressive behaviour and poor prognosis (Cheville et al, 2004).
Not only is there need for differentiation in indicator achievement goals depending on the needs of the patient group, questions may also be asked about the relevance and the completeness of the QOF indicators.
Immunostaining for collagen type I, an indicator for chondrocyte de-differentiation, indicated that stimulation inhibited its production.
Upregulation of pluripotency markers and downregulation of differentiation markers are indicators of somatic cell reprogramming.
These factors mostly relate to cellular differentiation, while alternative indicators of the metabolic status of tumour cells, such as oxygenation, are relatively sparse (Brizel et al, 1997; Vaupel and Hoeckel, 1999).
More significantly, we found that 2BP severely inhibited bone nodule formation, a later marker of osteoblast differentiation and an indicator of osteoblast bone forming activity (Fig. 2D).
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