However, as shown in the previous section, the lack of large-scale geographic differentiation in this study does not preclude the existence of a fine-grade genetic differentiation caused by a small-scale temporal patchiness or cryptic spatial structure in the spawning stock (Dannewitz et al. 2005).
A critical difference in the cell culture conditions in that study was the maintenance of hNP cells in the presence of LIF prior to differentiation; in the current study, hNP cells were maintained in the absence of LIF until initiation of differentiation.
In addition, JWA has significant predictive power for its correlation with tumor differentiation in the present study, which was known as an important factor for tumor progression.
However, high P-values and relatively marginal differences in these biomarker levels with regard to diagnostic and prognostic differentiation in the present study cohort of 116 patients suggest that there might not be a real clinically relevant difference.
In this context, it is of note that two of the four carcinomas with neuroendocrine differentiation in the present study only expressed chromogranin A or synaptophysin and not both of these markers, arguing for a routine immunohistochemical panel including both chromogranin A and synaptophysin.
Microsatellite analysis of whale sharks sampled primarily at feeding aggregations around the world showed little genetic differentiation in this study.
However, the resolution of genetic differentiation in these studies is limited because of the relatively low marker density.
Despite its potential for promoting the keratinocyte differentiation, in our study, the epidermal thickness of Brn2-injected rat skin significantly increased with the increased differentiation in the spinous and granular layers.
To contest this gendered differentiation in the sphere of study and work, women must recognize that the set of beliefs supporting this sexual segregation is simply a "custom and corruption of our time" [FI, p.426].
