Exact(3)
Diploid and hexaploid individuals often co-occur in mixed populations, where they are spatially and ecologically segregated at both the meso-scale (altitudinal differentiation, exposure of the growing site) and the micro-scale (cover of vegetation and bare rock).
With the onset of cell differentiation, exposure to 10 μM Ag+ evoked even greater inhibition of DNA synthesis and more oxidative stress, selectively impaired neurite formation without suppressing overall cell growth, and preferentially suppressed development into the acetylcholine phenotype in favor of the dopamine phenotype.
Activation of Notch signalling also has the potential to increase Mk differentiation: exposure to Notch ligands or transduction with the Notch1 intracellular domain increased megakaryocytic output in sorted murine stem and progenitor cell populations in vitro, and Notch inhibition reduced the number of megakaryocyte-erythroid progenitors (MEPs) and megakaryocytes in vivo (Mercher et al, 2008).
Similar(57)
Thus, we did not further examine EB formation with only post-differentiation exposure to the epimutagen mixture.
When cultured on dermal fibroblasts, the cord epithelial cells were able to differentiate in vitro into a stratified multilayered epithelium expressing molecules characteristic of keratinocyte differentiation after exposure to air, and maintaining the expression of keratins K18 and K19, typical of the umbilical cord epithelium.
Following the light-induced DNA transfer into cells, cell differentiation with exposure to two kinds of PACAP peptides was observed to determine the cell phenotypic change after PAC1R gene knockdown.
Based upon the results, it can be concluded that neuronal induction had initiated the early steps of neuronal differentiation, while exposure of the cells to non-neurological stressors had caused necrotic alterations.
Under standard culture conditions these stem cells can be maintained with minimal spontaneous differentiation, but exposure to all-trans-retinoic acid (RA) for 1 2 days is sufficient to cause almost all the cells to commit to differentiate irreversibly, after which they generate a mixed culture of neurons and other cell types.
However, even in the absence of Polycomb, levels remained well below those observed after differentiation and exposure to RA.
HL-60 cells are neutrophilic promyelocytes that can undergo granulocytic differentiation upon exposure to compounds such as DMSO (dimethylsulfoxide).
Results: We observed significant attenuation of osteoblast differentiation after exposure of BMSCs to arsenic trioxide (0.5 or 1 μM).
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