Sentence examples for differentiation decisions from inspiring English sources

(2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.

We hypothesize that the network provides a homeostatic mechanism balancing HPC/HSC growth control and differentiation decisions in response to microenvironment and other external stimuli.

In this review, we will highlight recent research that has defined roles for metabolism in the organization and interpretation of the genome and how this influences cellular differentiation decisions.

Other studies identified some of the mechanisms coordinating cell cycle and differentiation decisions in the retina.

The major function of Notch signaling is to regulate differentiation decisions.

In the retinal progenitor cells, differentiation decisions are coupled to regulation of cell cycle.

In this way, the interplay between the different STATs allows the cell to sense complexities in the cytokine environment and the resultant cell phenotype could lie somewhere along a continuum rather than representing a decisive differentiation decision.

TGF-β signaling influences the proliferation vs. differentiation decision of germline stem cells in parallel to the GLP-1/Notch pathway.

However, the proposed deterministic model failed to describe the heterogeneity in the differentiation decision of the HSCs.

Thus, Ascl1 is expressed at the onset of NA neuron differentiation but is rapidly downregulated, and hence is well placed to play a role in the progenitor maintenance versus differentiation decision specifically at these early developmental stages.

To better understand how puf-8 may be regulating the proliferative fate vs. differentiation decision, we sought to determine where puf-8 may function in the genetic pathway regulating this decision by performing genetic epistasis experiments.