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Coefficient of variation (CV) and phenotypic differentiation coefficient (VST) were 27.2% and 27.3% respectively.
Likewise resolution into three distinct populations by PCoA (Figs. 7 and 8), and the observed gene differentiation coefficient (0.49) and gene flow statistic (0.51), highlighted some chances of genetic exchange.
Nei's gene diversity (ĥ; (Nei 1973)), Shannon's diversity index (Î; (Lewontin 1972)), within-population genetic diversity (Ĥ pop), total genetic diversity (Ĥ sp), within-population gene diversity (Ĥ S), total gene diversity (Ĥ T), genetic differentiation coefficient (Ĝ st ) and gene flow (Ň m) were quantified.
These endometrial cells survive the metastatic process and the condition in ectopic sites due to their high differentiation coefficient.
We now investigate the likelihood of cancer cell survival during the metastatic process and the role of the differentiation coefficient in the establishment of metastatic lesions.
This simulation describes one cascade of tumor development and evolution of a dominant subpopulation, where the differentiation coefficient in some cells is already zero (completely transformed).
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For differentiation coefficients (F ST ) among countries, the values were higher between Senegalese landraces and any other countries (Fig. 4a).
These observed genetic differentiation coefficients were relatively high by comparison with those of closely related species (see [ 70– 70]).
Figure 2 shows the pairwise differentiation coefficients (F ST) estimated for the 5 parasite populations according to the 6 microsatellite loci and the complete dataset (n = 281).
The evolution of each cell's affinity a at time t is given by: (1) a t + 1 = min a t ⋅ r, a max a t / d a t in A in Ω for transistions A → Ω and (Ω → A ) Here r > 1 and d > 1 are the regeneration and differentiation coefficients, respectively.
The differentiation coefficients between each pair of P. infestans populations (FST) were estimated according to Weir and Cockerham (1984) using genepop 4.0.7 (Raymond and Rousset 1995), and their statistical significance was tested with the exact G-test (with default Markov chain parameters) implemented in genepop.
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