Sentence examples for differentiation characterised from inspiring English sources
Similarly, the low recovery properties of histone H2B and H3 ([ 31], and Figure 2a,b) were significantly reduced when proliferating mESCs were induced to neuronal differentiation, characterised by a cell cycle block in G0 phase [ 31].
When hESCs are cultured directly on tissue culture polystyrene (TCP) their distinct phenotype is quickly lost with cells undergoing spontaneous differentiation characterised by a change in cell morphology and loss of pluripotency markers, such as OCT4 and NANOG [ 1, 3].
A combination of complementary approaches to assess the kinetics of the appearance of each subset during development allowed us to obtain new insights into these terminal stages of differentiation, characterising their gene expression profiles at a pan-genomic level, their distinct surface receptor patterns and their prototypic effector functions.
As shown in Table 1, mass spectrometry signals responsible for differentiation were characterised by the values of the VIPs (where a VIP value of >1 is regarded as significant) from the PLS-DA analysis [4].
Those tumours with HF differentiation were characterised by high expression of both nuclear VDR and nuclear β-catenin, particularly within the aberrant follicles (Figure 5D).
Later stages of cone differentiation are characterised by enrichment of opsin in their outer segments.
Differentiation was characterised by flattening of the cells, formation of brush borders (epithelium-like structure) on apical HT-29 cell surface and tight junctions between adjacent cells.
In contrast to conventional skin-derived iPSCs, Pro-iPSCs showed a vastly increased ability to generate prostate epithelial-specific differentiation, as characterised by androgen receptor and prostate-specific antigen induction.
Marked regulation of genes involved in lipid and glucose metabolism and pathways producing NADPH and glycerol-3-phosphate (G3P) was seen during the terminal differentiation, also characterised by diverse stress responses.
Given that CCNG2 deeply participated in cancer proliferation, invasion, chemoresistance, and differentiation, which characterise CSCs, CCNG2 may be involved at least partially in the maintenance of CSC-like spheroid cells.
