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Human pluripotent stem cell (hPSC) differentiation aims to mimic development using growth factors or small molecules in a time-dependent and dose-dependent manner.
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"I think its interesting that they're going for a point of differentiation, aiming for the high-end of the e-ink market," said Philip Jones, editor of the Bookseller magazine.
This intimate interaction maintains MSCs in their quiescent state or provides signals toward differentiation, aiming to repair damaged tissues.
Differentiation therapy aims to induce cancer cells to differentiate by treatment with differentiation-inducing agents [ 46, 47].
Differentiation therapy aims to induce the cancer cells to differentiate and maturate continuously by treatment with differentiation-inducing agents.
A clear differentiation between aims and hypotheses formulated before data collection, and analysis and interpretation of the study findings and their publication thereafter, is central to science.
A clear differentiation between aims and hypotheses formulated before data collection, and analysis and interpretation of the study findings and their publication thereafter, central to science, should be agreed within the whole group carrying out the research.
Among the factors influencing population differences in allele counts (differentiation), the model aims at distinguishing locus-specific from population-specific factors, such as migration or drift [ 17].
However, cancer cells may instead be coaxed into becoming normal cells by differentiation therapy, which aims to reactivate endogenous differentiation programs in cancer cells to resume the maturation process and eliminate tumor phenotypes (Fig. 1).
We followed up by investigating intra-specific patterns of genetic diversity and differentiation, our specific aims being to i) assess the level of genetic diversity in different parts of the distribution range of each species, ii) identify potential population structure within species, and iii) use allele frequency data to look for signs of demographic events in the history of the species.
Several approaches have been used to achieve in vitro neural differentiation from hPSCs, aimed at generating regionally specified neural progenitors or differentiated neurons/glial subtypes [ 13].
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