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Interestingly, a recent study identified differentially methylated regions in post-mitotic cells as shown in monocyte cultures differentiating to dendritic cell or macrophage populations [ 50].
However, there has been no analysis of the expression profile of mRNAs in pleomorphic slender forms (i.e. those capable of differentiating to stumpy forms), in vivo generated stumpy forms or cells undergoing synchronous differentiation from stumpy to procyclic forms.
Second, competing around (unique) technical features is pretty short-lived; they are either insufficiently differentiating to the consumer and/or get copied in your competitor's next release.
Our data suggest an ability of host stem cells to be recruited into the scaffolds with the capability of differentiating to muscle cells.
Human embryonic stem cells (hESCs) have the advantage of differentiating to all cell types in the body and high proliferation capabilities.
You might argue that being container-native may not be sufficiently differentiating to produce lasting business, and that container-native may become a subset of functionality offered by legacy vendors.
NPCs express Nestin and Sox2 and are capable of differentiating to mature postmitotic neurons and astrocytes [29].
This suggests that Δrps13 can maintain functions vital for persistence while neither replicating nor differentiating to encysted bradyzoites fully.
CD184+ has been described for the isolation of neural cells capable of differentiating to neurons post-FACS [27].
When satellite cells are activated by muscle damage, they undergo rapid cell divisions before differentiating to form myofibers.
In addition, MSCs were capable of differentiating to osteogenic, chondrogenic and adipogenic lineages (data not shown, www.clonetics.com).com
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CEO of Professional Science Editing for Scientists @ prosciediting.com