Now, new findings by planetary scientists at MIT and other institutions suggest that may not be the case: that many asteroids with cores might be only partially differentiated, with their outer regions largely unmelted.
When CPN-MSCs were cultured in osteogenic, adipogenic, and chondrogenic differentiation medium for three to four weeks without any further CPN addition, they differentiated with their fluorescent labels intact.
A gene-signature, as described in previous studies [3], [5], is a concise list (threshold applied by a mathematical variable) of statistically differentiated genes with their regulation status (up or down) specified, which collectively characterise the biological state of a researcher's interest.
Since stem cells proliferate throughout life they are more susceptible to accumulate oncogenic mutations than differentiated cells with their comparatively short life span [ 7, 8].
hybridisation is likely to cause more dramatic phenotypic changes than genome doubling per se because it results in transcriptional effects following the combination of differentiated genomes, with their divergent regulatory machinery, into a common nucleus (reviewed in [ 80]).
The objectives of the experiments were to show whether it was possible to detect process contamination using the BonNDTinspect system as well as whether these contaminations can be differentiated with reference to their concentration and whether a conclusion can be drawn based on the result of wetting on the adhesiveness.
This experiment was repeated in PC12 cells differentiated with NGF to their neuron-like phenotype: here we found an even stronger difference between the two kinases (data not shown).
Since most of the primary tumors studied in the LHC-BS analysis had a well or moderately differentiated histology, we obtained 39 well-to-moderately and 39 moderately differentiated HCCs together with their matched adjacent tissues (Additional file 10: Table S6).
STIM1 and Orai1 expression became down-regulated in differentiated cells, consistent with their respective roles as ER Ca2 + sensor and store-operated Ca2 + channel (SOC).
Similarly, sustained caspase-3 activity and AR expression levels were both increased in a time-dependent manner, which was more evident in differentiated ESCs, compared with their undifferentiated counterparts.
The hitherto undescribed co-regulation of Mb with ER α by oestrogen likely underlies the co-expression of ER α with Mb in differentiated luminal cells with their reduced proliferation, which, in turn, might explain the favourable prognosis of Mb-positive tumours.
