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To determine the effects of LPA and S1P on cell survival during neuronal differentiation, hNP cells were differentiated via bFGF withdrawal for 14 days.
This is a significantly different result than previous bacterial strain differentiations, since the strains were physically separated and concentrated as opposed to differentiated via dielectrophoretic forces.
Inter-laminar damage at the interface and the intra-laminar damage close to the same interface can be differentiated via polarization-resolved imaging.
SV6, SS and SS V interiors are differentiated via the application of circular air vents.
The up-regulation of VASA expression was observed in ES cells differentiated via spontaneous EB formation.
In brief, both lines were differentiated via embryoid body (EB) formation and treatment with or without retinoic acid.
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Deletion of Fgfr1, in osteochondro-progenitor cells in mice (via Col2-cre), leads to increased proliferation and delayed differentiation, and matrix mineralization of osteoblasts, while inactivation of Fgfr1 in differentiated osteoblasts (via Col1-cre) causes accelerated osteoblast mineralization differentiation.
In vertebrate embryos, neural crest cells represent a prime example of a cell type that rapidly transits from an undifferentiated to differentiated state via progressive gene regulatory changes1.
Based on specific genetic alterations found in the different types of DCIS, a more likely scenario is the evolution of well-, moderandly, and poorly differentiated DCIS via distinct pathways.
Our view is that there will be many technical improvements over the next few years in the method of producing patient-specific differentiated cells (via reprogramming, transdifferentiation or partial reprogramming) to allow all of the relevant studies to be executed.
However, our results suggest that highly divergent regions between populations undergoing little or no introgression might sometimes represent so-called 'incidental islands' that do not harbor genes affecting reproductive isolation [ 31, 33], but that have nonetheless differentiated strongly via genetic drift.
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