Sentence examples for differentiated to human from inspiring English sources

d, BM cells (engrafted from donor βAβA#1 and βSβS 1) collected from engrafted mice were in vitro differentiated to human erythroid cells for HbF level analysis by HPLC.

Generation of PINK1 knockout mice Primary embryonic mouse cultures Table S1 Antibodies SDS-PAGE and immunoblotting Production of stable cell lines Measurement of total and reduced glutathione Live cell imaging ETC activities We first sought to validate the use of the human NSC model, differentiated to human midbrain neurons, as a useful model to test PINK1 function.

The ensuing mammary tumors show a solid growth pattern with pushing margins, and are highly proliferative, poorly differentiated and similar to human basal-like breast cancers (ER-, PR- and human epidermal growth factor receptor (HER) 2-negative).

In addition, it has been suggested that P53 gene mutations trigger progression from differentiated to anaplastic carcinoma in human thyroid glands [ 51]; P53 is particularly hypermutable in thyroid cancer [ 52].

Genome-wide microarray transcriptional profiling was used to compare LESCs to differentiated human CECs.

However, the murine tumor is a lowly differentiated to undifferentiated carcinoma whereas the human specimens manifest moderate to low differentiation.

Human iPSC cells were differentiated to neurons with treatment of neuronal differentiation media.

The authors generated a mouse model with aberrant expression of GREM1 in the intestinal epithelium, which resulted in the formation of crypt structures in the differentiated villus compartment, similar to human HMPS.

Histological analysis revealed that the tumors developed by cen3tel cells at the first and second tumorigenic phases were pleomorphic sarcomas (Fig. 1B and C), those developed by phase III cen3tel cells showed a hemangiopericytoma-like vascular pattern, similar to human poorly differentiated, round-cell synovial sarcoma (Fig. 1D).

Recent work further describes poorly differentiated cells with morphology similar to human GBM cells (Shapiro et al., 1970; Zagzag et al., 2000).

These data indicate that hSC might not be susceptible to damaging effects of RIBE signaling compared to differentiated adult human somatic cells as shown previously.