Sentence examples for differentiated them into from inspiring English sources

Mitne-Neto and colleagues successfully reprogrammed fibroblasts from an ALS8 patient into pluripotent stem cells and differentiated them into motor neurons [ 85].

Alipio et al. [ 52] derived iPS cells from murine skin fibroblasts and differentiated them into insulin-secreting β-like cells in vitro that responded to glucose stimulation under physiologic or pathologic conditions.

In order to correlate lack of Prf1 expression with the Th17 transcriptional program, we purified CD3+CD4+CD44-Foxp3- naïve T cells from Foxp3gfp.KI mice and stimulated them without exogenous cytokines (Th0) or differentiated them into Th1 cells or Th17 cells.

Here, researchers created stem cells from patients with a rare neurological disease, familial dysautonomia, and then differentiated them into the specific neurons (shown labeled with red and blue markers) affected by the disease.

To confirm the neurite phenotype observed in NSC-34 cells, we transfected the constructs into the rat forebrain neural precursors and then differentiated them into neurons.

To evaluate the potential of our iPSC cell lines for understanding the complexity of the 3 laminopathies, we differentiated them into secondary fibroblasts.

Stem cells and the cells differentiated from them into specific tissue lineages can be cultured and/or differentiated on dishes with immobilized external stimulus-responsive polymers.

hIPCs expanded in vitro were shown to express MSC markers, and a fraction of them differentiated in vitro into mesodermal cell types, such as adipocytes and osteocytes [17].

We can conclude that expression of RHOX2A or RHOX4B at a high level is incompatible with an undifferentiated ES cell phenotype possibly driving them into a differentiated cell type that has a significantly reduced viability and/or clonogenic potential.

The CCR8 CCL8 (MCP-2) axis plays a major role in the chronic inflammatory process in response to allergens (32, 35, 36) by specifically acting on highly differentiated TH2 cells and recruiting them into skin and draining lymph nodes.

Forced expression of four transcription master-regulators, Oct3/4, Sox2, Klf4 and c-Myc (OSKM), were able to overcome the epigenetic traits of differentiated cells and to revert them into the naive pluripotent state.