Sentence examples for differentiated t from inspiring English sources

From our data, we cannot determine whether the observed Th1 phenotype increase is due to the reprogramming of differentiated T cells or to the direct differentiation of naïve T cells.

A summary of major helper T cell subsets and the cytokines that promote their development is presented in Figure 2. In recent years, evidence is mounting to suggest that particular cytokine combinations may affect not only the differentiation of naïve TH0 cells but also that of differentiated T cells towards various helper subsets.

Recent studies have challenged the rejuvenation of differentiated T cell by various approaches.

Importantly, our new medium effectively expanded more differentiated T cells from multiple myeloma patients in the absence of serum.

(e) Immunofluorescence staining of differentiated T (5:7 -mESCs with anti-Nestin (ectodermal markers), anti-Tuj1 (ectodermal markers), anti-Myosin (mesodermal marker) and anti-Gata4 (endodermal marker) antibodies.

The occurrence of mutations in terminally differentiated T cells may discriminate a benign disorder from a malignant transformation (such as leukaemia or lymphoma), because terminally differentiated effector-memory cells have limited proliferation potential.

Although great efforts and progresses have been made in understanding IL-10 production during T-cell differentiation, the mechanisms that regulate IL-10 production by differentiated T-effector cells are still unclear.

In addition, CD3+CD56+ cells bear the CD27+CD28− or CD27−CD28− phenotype because they belong to terminally differentiated T-cell populations, whereas CD3+CD56− cells are subjected to early differentiation and mainly express the CD27+CD28+ and CD62L+ phenotypes [ 22, 23].

Finally, the CD123 CAR was efficiently expressed in CD34+ cells and proved to be functional when expressed on differentiated T-cells.

The second function, observed under all the experimental conditions we deployed in this study, contributes to the production or secretion of cytokines from committed, differentiated T-helper cells.

Differentiated T-cells, defined by the CD45RA+CCR7− phenotype, exhibited the lowest number of IL-7 receptor molecules (Figure 4) and central/peripheral memory T-cells (CD45RA−CCR7+ or CD45RA−CCR7−) exhibited the highest IL-7R density.