To examine the outcomes and risk factors in pediatric differentiated thyroid carcinoma (DTC) patients who were defined as TNM stage I because some patients develop disease recurrence but treatment strategy for such stage I pediatric patients is still controversial.
Evaluate current accepted risk factors for well-differentiated thyroid carcinoma, and develop a predictive model to determine one's risk of malignancy given a thyroid nodule.
Mortality data are a product of both incidence and case fatality, and do not allow risk factors to be individually differentiated.
Patients with risk factors including tumour poorly differentiated, T4 stage, tumour perforation/obstruction, number of lymph nodes examined <12, or lymphatic/vascular invasion were considered as high-risk stage II cases.
Patients with risk factors for relapse (tumor poorly differentiated, tumor perforation, number of lymph nodes examined <12 or lymphatic/vascular invasion) were considered high-risk stage II cases.
This study evaluates the incidence and risk factors of complications in patients submitted to thyroidectomy for differentiated thyroid carcinoma in a cancer hospital with residency training.
[ 12] These risk factors include lymph node sampling below 12, a poorly differentiated tumor, vascular or lymphatic or perineural invasion, a pT4 stage, and intestinal occlusion or perforation on clinical investigation [ 9].
These risk factors include <12 lymph nodes discovered after surgery, poor prognostic features (poorly differentiated histology), lymphatic/vascular invasion, bowel obstruction, perineural invasion, localized perforation, and close or positive margin.
Risk factors for peritoneal recurrence have been reported to include an undifferentiated histological type, infiltrative tumour growth and serosal invasion, while risk factors for haematogenous recurrence have been reported to include a vessel invasion, differentiated histological type and expansive tumour growth (Maehara et al, 1996; Yoo et al, 2000; Ohno et al, 2003; Roviello et al, 2003).
Reported risk factors for haematogenous recurrence, on the other hand, include blood vessel invasion, a differentiated histologic type and expansive tumour growth (Maehara et al, 1996; Yoo et al, 2000; Ohno et al, 2003).
