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However, if HSC differentiation is sufficiently fast (a≪̸1), the clonal distribution in the progenitor and differentiated pools may be modified.
Total FAs of T. brucei can be separated in two well differentiated pools by gas chromatography (Fig. 1): pool 1 which includes middle- and long-chain FAs, and pool 2 formed by C20 and C22 PUFAs with up to six double bonds.
This date far precedes domestication, supporting independent domestications of indica and japonica from pre-differentiated pools of the wild ancestor.
All renewing tissues require stem cells to repopulate the differentiated cell pool that is lost as a result of physiological cell turnover.
Our clonal tracking analysis revealed that individual clones of HSCs contributed differently to the final differentiated blood pool in rhesus macaques, consistent with mouse and human data.
To consider the entire problem stochastically, the variability described by probability distribution P b would have to be propagated forward to the differentiated cell pool as well.
In the introduced range, founder effects tend to increase among-population differentiation and separate introductions may establish differentiated gene pools in different sites through founder effects, subsequent drift and/or responses to selection [9], [10].
The 3-clade structure, and its relationship to disease, is poorly understood but for it to arise and be maintained requires differentiated gene pools.
F1 crop wild hybrids combine genetically differentiated gene pools.
Long-distance dispersal may tend to connect distant populations, homogenizing differentiated gene pools.
With glacial retreat, isolated populations may reconnect leading to gene flow between differentiated gene pools.
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