Sentence examples for differentiated phenotype of from inspiring English sources

The differentiated phenotype of melanocytes must be due, at least in part, to differential transcription of melanocyte-specific genes [ 30].

For keeping highly differentiated phenotype of eukaryotic cells in ex vivo culture conditions, different kinds of microgravity-simulating rotary-wall vessel systems are employed.

The first objective of PROMOCART was to determine if bone morphogenetic protein (BMP -2 could maintain or restore the differentiated phenotype of human chondrocytes.

The aim of this study was to examine the effect of three-dimensional (3D) architecture on the differentiated phenotype of human smooth muscle cells derived from the stroma of the lower urinary tract.

Importantly, the expression of SM α-actin, a differentiated phenotype of SMCs, was upregulated by 2.5-fold in VSM tissues engineered under the mechano-active condition, compared to VSM tissues engineered in the static condition.

Inhibition of proliferation, cell cycle arrest, increased motility, and altered adherence are aspects of the differentiated phenotype of villus epithelial cells, which withdraw from the cell cycle at the crypt/villus interface, migrate to the villus tips, and are subsequently shed by loss of contact with the epithelium and the underlying extracellular matrix.

Here we report two-dimensional cell sheet manipulation (2D CSM) of heterotypically co-cultured lung cell sheets and the maintenance of differentiated phenotypes of lung epithelial cells over prolonged periods of up to 70 days.

The differentiated phenotypes of the cells used in the experiments were confirmed through macroscopic observation and by expressions of type II collagen and aggrecan mRNA (data not shown).

Although ESSCs have shown the differentiated phenotypes of astrocytes and neurons under the influence of epithelial growth factor (EGF) and fibroblast growth factor (FGF) [ 5, 6], their long-term lineage plasticity in vitro is yet to be characterized.

Considering the well-differentiated phenotype of HELUs, another apparent paradox was the underexpression of ITGA6 and ITGB4, which respectively encode α6 and β4 integrin, the two main components of laminin receptor [ 40].

Wnt3a-treated cells retained a differentiated phenotype, irrespectively of Dll4 addition.