Suggestions(2)
Exact(7)
Testing population differentiation, 11 pairs of populations were found non significantly differentiated out of the 741 tests performed: AA5 with AA6, AA9 with AA10, SF8 and PS, PS and SF8, AA10 with SF8 and PS, AB with BA, APPAL with QH, AUX with TDN, SFA97 with SFB98.
This indicates they maybe differentiated out of the same source.
Furthermore, in SLE patients a significantly reduced number of macrophages differentiated out of the stem cells.
Heterophils, lymphocytes, monocytes, eosinophils, azurophils, and basophils were differentiated out of 100 cells counted.
Macrophages were differentiated out of bone marrow cells using 15 ng/mL recombinant murine macrophage colony stimulating factor (M-CSF; R&D Systems).
The defective clearance of dying cells in a subgroup of SLE patients seems to be an intrinsic defect because fewer macrophages differentiated out of stem cells, and some of the generated phagocytes also showed reduced uptake efficiency.
Similar(53)
An almost identical low hazard of relapse was observed between patients with well-differentiated out-of-cycle tumours who are often spared chemotherapy and those with high-grade tumours exhibiting a G1-delayed/arrested phenotype.
It is of note that high-grade tumours with the G1-delayed/arrested phenotype showed an identical low risk of relapse compared with well-differentiated out-of-cycle tumours (HR=1.00 (0.22–4.46), P=0.99).
Intriguingly, an almost identical low hazard of relapse was observed between well-differentiated out-of-cycle tumours and high-grade tumours exhibiting a G1-delayed/arrested phenotype (phenotypes I and II) (HR=1.00 (0.22–4.46), P=0.99; Figure 5).
This is in keeping with our observations in in vitro assays and self-renewing tissues that geminin is also tightly downregulated as cells enter quiescent (G0) and differentiated out-of-cycle states (Eward et al, 2004; Kingsbury et al, 2005; Barkley et al, 2007; Williams and Stoeber, 2007).
In the presence of unfavourable conditions or inhibitory signals, cells can normally withdraw from the cell cycle into quiescent (G0), terminally differentiated or senescent out-of-cycle states, a characteristic feature of most of the functionally differentiated cells of the human body (Stoeber et al, 2001; Blow and Hodgson, 2002).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com