Developing neurons travel toward the olfactory bulb along the RMS via glial tubes, which mark the division between the differentiated nervous tissue and the tissue with embryonic characteristics.
Despite of the small cell number C. elegans exhibits complex tissues such as intestine, muscle, hypodermis, gonad, and a fully differentiated nervous system.
Planarians exhibit much of the complexity of vertebrate systems, including a well-differentiated nervous system (with most of the same neurotransmitters as human brains), eyes, brain, three body layers, and bilateral symmetry.
Since C. elegans has highly differentiated muscular, nervous, digestive and reproductive systems, and yet is comprised of only 959 optically transparent somatic cells, we determined the spatial distribution of hmt-1 expression and related it to the expression pattern of its homolog in humans.
Both genes are required for proper nervous system development, with the knockdown of either causing a loss of differentiated neural cells.
Neuroblastoma (NB) is a pediatric tumor of the postganglionic sympathetic nervous system that develops from immature or de-differentiated neural crest-derived cells.
He chose the worm because it was a multicellular animal with properly differentiated organs (a nervous system, gut and so on) that consisted of only a few hundred cells.
They have neither body cavities nor differentiated organs, such as nervous and gastrointestinal systems.
They have neither body cavities nor differentiated organs, such as nervous and gastrointestinal systems (Fig. 1A).
During organogenesis in the central nervous system, differentiated astrocytes are characterised by a high expression of GFAP, a change from a polygonal shape to a stellate shape, and a low rate of proliferation (Wang et al, 1994).
In the hydrozoan Clytia hemisphaerica, five SoxB orthologues have been described; their expression is associated with both stem and differentiated cells of the nervous system, but there has been no functional characterisation of these genes (Jager et al., 2011).
