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Here, phylogenetic analysis of the conserved tRNA-like regions of the 93 newly described CanSINEs reveal two distinct subfamily lineages defined by time of emergence within Felidae and further differentiated into subtypes marked by specific sequence motifs and adaptive reverse transcriptase promoter sites.
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Seven of these types were differentiated into two subtypes with the second-generation membrane, while spb-7, the most prevalent in Spain, was further differentiated into eight subtypes.
This type of TR can be even further differentiated into two subtypes depending on the usage of the rare amino acid selenocysteine (Sec or U) in the penultimate position in place of Cys2.
The working alphabet is composed of four types of objects (also differentiated in subtypes) summarized below the Venn diagram.
In most cases, iPSCs were differentiated into disease-relevant subtypes of cells exhibiting certain disease features.
The latter was differentiated into static and dynamic subtypes.
The phenomenon of IUGR can be further differentiated into symmetric and asymmetric subtypes based on recent observations that the severity of long-term morbidities differ according to body proportionality (Gluckman and Pinal 2003; Villar et al. 1990).
Type A is divided into subtypes, which are differentiated mainly on the basis of two surface antigens (foreign proteins)—hemagglutinin (H) and neuraminidase (N).
The last category consists of pleomorphic liposarcoma. 1 At clinical presentation these tumors range from small superficial low-grade tumors to large infiltrating poorly differentiated retroperitoneal tumors. 2 Differentiation between lipomas and liposarcomas and the classification into subtypes is essential in tailoring treatment and for prognostic information.
Many serotypes are distinguished into differing subtypes based on amino acid sequence, and many subtypes are further differentiated into toxin variants.
Therefore, H1N1 represents a subtype of influenza A. This subtype is further differentiated into strains based on minor variations in RNA sequence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com