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They can originate from progenitors resident within WAT that are differentiated in response to browning stimuli a process known as de novo differentiation (Wang et al. 2013).
In plants, proper seed development and the continuing post-embryonic organogenesis both require that different cell types are correctly differentiated in response to internal and external stimuli.
In conclusion, the cells differentiated in response to NaB, as indicated by the downregulation of Oct4, and seemed to gain an epithelial identity and to express known liver markers.
Tregs are a subset of T cells controlled by the master transcription factor Foxp3 and differentiated in response to TGF- β [ 40].
A total of 164 proteins were significantly modulated upon doxorubicin stimulus, whereas 162 molecules were markedly differentiated in response to etoposide (Fig. 2b).
We found that chorionic girdle cells expressed the receptors for BMP4 in vivo and functionally differentiated in response to BMP4 in vitro.
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Stem cells grown in minimal media that had been supplemented with conditioned media from fibroblast feeder cells produced a mixture of undifferentiated and differentiated colonies in response to treatment with Anti-MUC1* (Fig. 8C,D) or bFGF (Fig. 8E,F).
In addition, we have listed the percentage of differentiated cells in response to control vector overexpression in Supplementary file 1 of the revised manuscript.
Old skeletal muscle loses its regenerative ability due to the failure of satellite cells (muscle stem cells) to divide and generate fusion competent myoblasts and terminally differentiated myofibers in response to muscle injury or attrition [ 1, 2].
Furthermore, 6-day LL-37-differentiated monocytes showed increased production of IL-1ra, IL-10, IL-12, IP-10, and GM-CSF than 6-day M-CSF/RANKL-differentiated monocytes in response to LPS (Figure 2K and Figure S2).
Differentiating HSPCs undergo progressive loss of differentiation capability in response to environmental conditions, resulting in terminally differentiated blood cells.
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