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It has a strong relationship with MVI but has no statistically significance on survival, since most of the patients were moderately differentiated in our study.
Based on alpha-synuclein deposits in skin biopsies as well as quantification of nerve fibers, two patterns of peripheral involvement could be differentiated in our study: IENFD and myelinated dermal fibers were reduced in a length-dependent pattern, whereas SP- and CGRP-immunoreactive intraepidermal fibers showed a non-length-dependent reduction.
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Although these differentiation models do not lead to terminally differentiated erythrocytes analyzed in our study, we note a high degree of similarity in the microRNAs seen during the earlier stages of erythroid differentiation investigated in these studies and the microRNAs reported here in mature erythrocytes.
Primary calvarial osteoblasts from mice lacking Nrf2 proliferated and differentiated normally in our studies, if even in a slightly enhanced fashion, when compared to control osteoblasts.
The use of non-fixed, differentiated, single fibres in our study should reflect a more physiological environment of the DHPRs, which are almost exclusively located in the t-tubules in skeletal muscle [49].
AF-6/afadin was expressed in all normal endometrial tissues and most well-differentiated endometrial adenocarcinomas in our study.
On this basis, blood vessels could be differentiated from lymphatic vessels in our study.
As clinical significance of MRP2 other than chemosensitivity, Gan et al (2010) reported that MRP2 expression was significantly higher in poorly differentiated ESCC tumours compared with moderate or well differentiated ones, which was not observed in our study.
The different GOF detected in CgPdr1 may alter in a positive or negative manner these interactions and thus could result in differentiated gene expression patterns as observed in our study.
Therefore, in our study, iPSCs were differentiated into renal lineage cells to obtain a sufficient number of RPCs.
A lower proportion of breast cancer among the AA women in our study was well differentiated as expected (CAU 76.8% vs AA 57.7%).
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