Your English writing platform
Discover LudwigSuggestions(1)
Exact(2)
The highly variable and differentiated gene expression patterns may explain the great extent of structural differentiation observed in complex organisms.
The different GOF detected in CgPdr1 may alter in a positive or negative manner these interactions and thus could result in differentiated gene expression patterns as observed in our study.
Similar(58)
Differential gene expression patterns were analyzed.
In contrast, blocking of miRNA let-7e in differentiated cells reversed these gene expression patterns, indicating the involvement of miRNA let-7e in renal epithelial cell differentiation.
Moreover, exposure to the epimutagen mixture only prior to inducing hiPSC differentiation affected cell morphology and gene expression patterns in differentiated EBs or neuronal cells, suggesting that the chemicals have a long-term effect on cellular differentiation.
On the other hand, differentiated HT29 and T84 cells showed gene expression patterns closest to tumor bulk derived cells.
As results, we found that most of the selected regulatory networks show complex oscillatory dynamics as chaotic dynamics in the early stage of development, from which multiple cell types with fixed gene expression patterns are differentiated.
Since the two cell lines were initiated from bone and brain metastases of prostate adenocarcinomas respectively [ 21, 22], an alternative explanation is that the progenitor cells that they are derived from had lost the gene expression patterns of differentiated cells from the prostate.
Intriguingly, high CD25 expression was strongly associated with gene expression patterns indicative of differentiated CTLs (P<0.0001), activated dendritic cells (P<0.0001), and a pro-inflammatory cytokine milieu (P<0.0001; Figure 4D).
DNA methylation patterns can be maintained by DNMT1 through replication and multiple cell divisions [ 61], and thus if they occur early in development they could be represented in multiple lineages including peripheral blood, but not be reflective of gene expression patterns in all differentiated lineages.
Addition of serum results in adherence to plastic and shifts gene expression patterns to resemble the differentiated parental cells.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com