Several previous studies have demonstrated that isolated chondrocytes exhibit a characteristically differentiated phenotype for the first few passages in culture (Benya and Shaffer, 1982).
In differentiated Caco-2/TC7 enterocytes, we identified for the first time LPCAT2 (lysophosphatidylcholine acyltransferase 2), involved in PC (phosphatidylcholine) synthesis, and 3BHS1 (3-β-hydroxysteroid dehydrogenase 1), involved in steroid metabolism, and confirmed their partial CLD localization by immunofluorescence.
In this study, we used the array platform GeneChip Human Genome U133 Plus 2.0 (HG-U133 Plus 2.0) to analyse the expression of a wide range of genes (>30 000) in well- and poorly differentiated thyroid tumours and, to correlate, for the first time, gene expression with BRAF, RAS, RET/PTC and PAX8-PPARG alterations.
The ACF and PACF for first-order differentiated data are shown in figure 3. The autocorrelations of the series after first-order differentiation is within 95% CI except for the first lag.
The model for the first hypothesis is that differentiated tubule cells undergo a dedifferentiation process.
These studies demonstrated for the first time expression of novel GPCRs in undifferentiated and differentiated ES cells and, in some cases, differential expression during ES cell differentiation.
For the first time, the role of mechanical stimulation in osteogenic differentiated intraoral MSPCs is the subject of investigation.
We demonstrate, for the first time, that high sHE4 levels correlates with an aggressive EC phenotype and may constitute an independent prognostic factor for poorly differentiated-ECs.
Second, the results obtained from the discriminant analysis are clearly differentiated for the two sub-samples (physicians and nurses, respectively).
