Sentence examples for differentiated fate from inspiring English sources

Rel2 was identified as a transcriptional corepressor of the indeterminant branching pathway and important in enforcing the differentiated fate of reproductive maize organs (Gallavotti et al. 2010).

Indeed, in the nervous system stable, as opposed to oscillatory, bHLH expression seems to be absolutely required for cells to exit the cell cycle and adopt a differentiated fate [ 27,28,29].

H1.1: GT1 > GT2 in Cell1 H1.2: GT1 < GT2 in Cell4 5 We do not use Cell2 3 in these specification, but if a cell has adopted a differentiated fate, cells in a higher sub-layer (on its right in the model) cannot be proliferating.

Indeed, in many stem cell lineages, the non-stem cell daughter initially has the potential to re-enter the niche and become a stem cell, indicating that it does not immediately commit to the fully differentiated fate (Morrison and Spradling, 2008; Simons and Clevers, 2011).

There are many examples of asymmetric divisions in biology, but one of the most notable is that of a stem cell, which characteristically produces one daughter that adopts a differentiated fate and another that remains a stem cell and proceeds to proliferate further (Knoblich, 2008).

The general pattern of division involves an asymmetric division at each larval stage, producing a posterior daughter that retains the ability to divide further and an anterior daughter that adopts a differentiated fate, most commonly contributing to epidermal tissue by fusing with the hyp7 syncytium (Sulston and Horvitz, 1977).

In summary, EpCAM expression fades, and its regulatory effects become muted as progenitor cells differentiate through their respective maturational lineages to adult, differentiated fates, accompanied with a drop in stem/progenitor activity, which suggests that the level of cellular differentiation and specialization, at least partly, depends on EpCAM expression (41, 53, 82, 99, 129).

The signaling pathways, protein interactions, cellular behavior, and the differentiated fates of experimental cells have been studied in vitro in detail.

The highest number (123) of SU transcription factors was found in the naive subtype – perhaps this implies a requirement for this number in maintaining a transcriptional programme poised for commitment to one of several possible differentiated fates.

These results strongly suggest that apically dividing d4Venus+ cells are indeed non-stem-like and committed to the neuronal lineage, and that these cells give rise to daughter cells that adopt differentiated fates.

Instead, these miRNAs may set the activation threshold prior to infection, causing the neonatal CD8+ T cells to differentiate more rapidly into effector cells, thus biasing them toward a terminally differentiated SLEC fate.