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These organisms appear to have differentiated considerably at the molecular genetic level without any major discernable morphological differences.
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If universal application is incorporated and all genera are considered, then the overall proportion of genera in which species in a pair were differentiated dropped considerably in ITS1 (45.8%) while trnH-psbA maintained the highest resolution (79.1%) and rbcL-a the second highest (62.5%) with values for all other loci at 50% or less.
We implemented four bioinformatic measures to discover genomic regions that are considerably differentiated either between two Han Chinese populations in the north and south of China, or across 22 populations in East and South-East Asia.
In consistency with Li and co-workers, we observed that p53-negative differentiated cells proliferated considerably faster than their wild-type counterpart.
Although the basic ability of eukaryotes to splice introns has remained conserved throughout evolution [ 6- 9], the splicing signals have considerably differentiated [ 10- 12], eventually to the degree that the splicing mechanisms of remotely related organisms are incompatible with each other.
As can be seen from the haplotype network analysis (Fig. 2), the two species are considerably differentiated, with one of the loci showing as many as 28 substitutions between alleles found in the two species (Fig. 2a).
We performed blast searches (TBLASTN and TBLAST) to determine if MEPE is present in non-mammalian or non-avian vertebrates (such as fish and amphibians), but we were not able to detect an orthologue in those lineages, suggesting that this gene may be considerably differentiated or even absent.
In contrast, radioiodine scanning has high specificity for recurrences of differentiated thyroid cancer but considerably low sensitivity [32].
While the low numbers precluded statistical comparisons, the CD8 T-cells of uninfected infants remained considerably less differentiated than those of most of their CMV-infected peers.
However, microsatellite data show that H. heurippa is a distinct species and not simply a geographic race of H. cydno; H. heurippa is considerably more differentiated than any other geographic populations of H. melpomene or H. cydno sampled in Panama, Colombia and Venezuela [ 26].
The vertebral column was well differentiated.
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