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DSM-III yielded an increasingly detailed and differentiated classification of disorders, subsumed under a new splitting of diagnostic areas (e.g. 'Neurotic Disorders' were dispensed with, but symptomatic remnants were distributed into the affective, anxiety, somatoform and dissociative disorders) (see Rogler, 1997).
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However, some markers may be relevant for the classification of differentiated follicular pathologies (FTA, FTC, PTC, OTA and OTC).
Because histological classification of intermediately differentiated DCIS versus well- or moderately differentiated DCIS is most challenging, we investigated whether gene expression profiling could be used to identify markers that could help in making this classification.
Multivariate analysis revealed that lymph node metastasis (HR, 2.03; 95% CI, 1.16 3.55; P=0.0133) and a histological classification of moderately differentiated adenocarcinoma (HR for papillary adenocarcinoma, 4.23; 95% CI, 1.08 16.50; P=0.0380) and poorly differentiated adenocarcinoma (HR for papillary adenocarcinoma, 13.22; 95% CI, 3.10 56.45; P=0.0005) were significant prognostic factors.
According to the degree of differentiation, NENs have been divided into well differentiated NENs and poorly differentiated NENs in the 2010 World Health Organization classification of tumors of the digestive system, with the former being termed a neuroendocrine tumor (NET), and the latter, a neuroendocrine carcinoma (NEC) [ 1].
Recently, a classification of iNPH differentiated between probable, possible and unlikely iNPH [ 10].
Biopsy specimens were histopathologically graded, and tumors were categorized as well, moderately, or poorly differentiated according to the WHO classification of tumors [ 16].
Tumors were classified as differentiated or undifferentiated types according to the classification of Nakamura et al.
WHO classification of liposarcoma is well differentiated, myxoid, round cell & pleomorphic types.
This demonstrated the relevance of our approach to the molecular classification of the main types of differentiated follicular thyroid pathology.
The patients were histopathologically classified as 118 differentiated (papillary, well-differentiated and moderately differentiated tubular adenocarcinoma) or 115 undifferentiated (poorly differentiated adenocarcinoma, mucinous adenocarcinoma and signet-ring cell carcinoma) according to the Japanese classification of gastric cancer (Japanese Gastric Cancer Association, 1998).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com