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The Colo 205 is a poorly differentiated cell line, and HT-29 is a well differentiated cell line (Kondoh et al, 1992; Laferte and Loh, 1992).
AGS, is a well studied poorly differentiated cell line (Barranco et al, 1983).
PLC/PRF/5 is a poorly differentiated cell line and derived from HCC of a patient with HBV.
Hec-1A cells were established from a 71-year-old woman and are considered a moderately differentiated cell line [ 28].
They both have much higher EGFR expression levels than highly differentiated cell line MKN-28 and responded to ganetespib much better than MKN-28.
DNA methylation and CG content negatively influence elongation rate, and could partially explain the difference between mESC and differentiated cell line derived elongation rates (Danko et al., 2013).
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It has been shown that migration and assembly of various primordia depend on expression of proteins that mediate differential cell adhesion events, and also that differentiated cell lines of ChP vary in expression of these proteins [43] [45].
We developed a robust method to obtain differentiated cell lines following the induction of hematopoietic differentiation of mouse ES cells and established five independent hematopoietic cell lines using the method.
Consistent with the known role of GATA3 in cellular differentiation, the highest GATA3 expression was observed in the more differentiated cell lines, Caco-2, SK-CO-15 and HT-29.
Vincristine, 5-fluorouracil (5-FU), and methotrexate (MTX) have been incorporated into the liposomes, and studies carried out using the differentiated cell lines Caco-2 and TC7, and with 150 histologically normal sections of human colon.
Our results showed that SINE coverage is positively correlated with CI frequency in both pluripotent and differentiated cell lines, while other TE families are not.
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