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Some of the identified genes with similar primary structures were differentiated by multiple sequence alignment with ClustalW [ 43].
Among the non-Beijing family strains, the six isolates harboring only one copy of IS 6110 were grouped into two clusters of 3 isolates each, and they were differentiated by multiple MIRU loci and spoligotyping.
Our findings, namely the relatively low number of large chromosomes in L. reali, variability in chromosome size in the other two species and the occurrence of multivalents in meiotic nuclei of all three species, suggest that the Leptidea karyotypes are differentiated by multiple chromosome fusions and fissions.
They rather suggest that the regions containing the ancestral trim16 and trim25 moved apart in the early fish evolution and were kept as synteny groups on two different chromosomes while most fintrims appeared and differentiated by multiple duplications in the fish lineages.
Both the P. dardanus engrailed locus and P. polytes doublesex have alternative alleles associated with different female mimetic morphs and these alternative alleles differentiated by multiple changes with a high ratio of non-synonymous to synonymous SNPs in the coding regions.
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The mixing of differentiated genotypes by multiple introductions is thought to be an important process in adaptation during invasion (Facon et al. 2008; Estoup and Guillemaud 2010).
Like the primary leaves, these leaves are fully differentiated and characterized by multiple linear segments.
The final identity of a differentiated neuron is determined by multiple signaling events, including activity dependent calcium transients.
Excluding the possibility of paralogs, incongruence caused by hybridization and lineage sorting could be differentiated by comparing phylogenies of multiple unlinked nuclear loci.
Both loss of function and "co-adapted" gene complexes formed by multiple alleles with differentiated functions (effects) are predicted to be frequent types of allelic diversity at loci that contribute to the genetic variation of complex traits in populations.
Our model suggests that both loss of function and "co-adapted" gene complexes formed by multiple alleles with differentiated functions (effects) should be frequent types of allelic diversity at loci that contribute to the genetic variation of complex traits in populations.
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