Sentence examples for differentiated back from inspiring English sources
These corrected iPSCs were then differentiated back into fibroblasts, and injected intradermally into mutant mice.
Human prostate and urinary tract tissue can be used to generate iPSCs that can be differentiated back into their parent organ lineages.
Blue-garbed Superman required a differentiated backing, and sodium vapour (yellow) light was used on the screen to yield a transparent background for the flight scenes in Mary Poppins (1964).
Our finding that HOXB9 inducing expressions of tight junction protein shed light on the hope that enhancing the level of HOXB9 in colon adenocarcinoma cells may help to drive the de-differentiated cells to differentiate back to epithelial cells that hold low growth and invasion potentials.
Reprogramming of a differentiated cell back to a naive pluripotent identity is thought to occur by several independent mechanisms.
The importance of the transcriptional regulatory network in establishing ESC self-renewal and pluripotency was elegantly demonstrated by Takahashi and Yamanaka [ 4], whereby introduction of four transcription factors Oct4, Sox2, Klf4 and c-Myc (OSKM) could revert differentiated cells back to pluripotency as iPSCs.
A free version would likely need to be differentiated and/or scaled back in order not to cannibalize sales of the revenue-producing version.
"The question is whether the mutations have a detrimental effect once the cells are differentiated and transplanted back in vivo, not whether they are present or not," he says.
What Dolly demonstrated was that it is possible to take a differentiated cell, turn back its biological clock, and make the cell behave as though it was a recently fertilized egg.
It is almost impossible to convert a fully differentiated mammalian cell back to the pluripotent state by only switching culture medium.
Haldane was the first to note that when two differentiated lineages come back into reproductive contact, the heterogametic sex (i.e., the one with two types of sex chromosomes) often shows reduced fertility [ 6].
