According to this study, the overall number of bivalent domains does not seem to change between ES cells and neural progenitors, as loss during differentiation is largely compensated by newly formed bivalent domains in differentiated cells at different states.
A major deviation from Models (1) and (2) is the presence of functionally differentiated alleles at different loci in a FGU.
These data indicated that loss of TACSTD2 could be a common phenomenon of poorly differentiated SCC at different anatomical sites.
The three main berry tissues, seed or endocarp, flesh or mesocarp and skin or exocarp, were differentiated at the different developmental stages, and their dissection was only possible after certain stages.
Interestingly, electron micrographs taken below the sloughing layers of the corneum exposed non-differentiated keratinocytes at different stages of nuclear disintegration, indicative of rapid keratinization [ 6].
Vannucchi and colleagues retrospectively followed 123 patients with differentiated thyroid cancer at different intervals during pregnancy.
The purpose of the separation period was to generate two partially differentiated populations that were at different genetic levels for important traits.
Differentiated neurons appear in small, isolated, bilaterally symmetrical clusters which give rise to specific structures, and the increase in differentiated neuron number occurs at different rates during development in the different clusters [ 33].
Genetically differentiated groups made transitions at different times even though they were the same age and shared a common hive environment (Calderone and Page 1988 , 1991 Pankiw and Page 2001).
NPBs are inactive and start to transform into fully differentiated, mature, functional nucleoli at different embryonic developmental stages, specific to a given species (e.g. 2-cell stage in the mouse).
