If during these trials treatment failures are not adequately differentiated from cases of exogenous re-infection, promising new drug candidates may be abandoned erroneously.
Our results suggest that certain options are not currently being adequately differentiated.
In addition, culture of these non-terminally differentiated cells requires a high level of skill to adequately maintain cellular homogeneity.
Adult podocytes are terminally differentiated glomerular epithelial cells that are unable to proliferate adequately to replace those lost in glomerular diseases [ 1, 2].
It is crucial that the malignant forms of neoplasms are diagnosed and differentiated from benign tumors as early as possible to treat patients adequately.
However since exfoliated cells are keratinized and terminally differentiated, it remains to be demonstrated that they have an active mRNA profile that adequately represents the molecular signature of cervical tissue.
We believe that the GFI has the potential to provide more differentiated information about the salience of specific frailty-related problems, and thus direct a more adequately focused program for the care and support frail older adults need.
Whereas, the effect of microenvironment (mE) factors, the behaviors of CSCs, progenitor tumor cells (PCs) and differentiated tumor cells (TCs), and the impact of CSC fraction and signaling heterogeneity, are not adequately explored yet.
Small lesions that are <1 cm in diameter and that have a well-differentiated histology (particularly those in the rectum, which tend to have a less aggressive course) may be considered adequately treated by complete endoscopic removal or transanal mucosal resection; however, the patient will require follow-up endoscopy to ensure this has been accomplished.
This approach was considered appropriate in the context of a proof of concept study as the artificial bone does have cortical and cancellous bone components that can be differentiated on CT images with sufficient accuracy, such that the screw purchase in either cancellous bone or cortical bone is adequately mapped to the model.
