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Interestingly, a recent publication suggests that following a transient period of c-Myc inactivation, at least some previously c-Myc activated suprabasal keratinocytes may differentiate to an extent sufficient to render them unable to re-enter the cell cycle after c-Myc reactivation [ 28].
Similar(59)
In vivo, after chemotherapy, the residual malignant CD34+CD38- cells are thought to differentiate, to a limited extent, producing leukemic cells with an immunophenotype, usually observed at diagnosis.
This system showed that MSCs could differentiate to a greater extent into osteoblasts on the fibronectin patches with side lengths of 300 nm or 1 μm compared to nonpatterned surfaces, in the absence of differentiation-inducing media [ 56].
Intracortical inhibition was also modulated but differentiates to a lesser extent only between perturbation conditions and unperturbed stance.
Satellite cells of 2 month, 6 month, and 12 month old mdx mice were capable of differentiating to a similar extent to age-matched wild type control animals in an in vitro proliferation/differentiation model.
It is important to note that despite their apparent ability to differentiate to some extent between leopard and snake chirps, green monkeys, like vervets (Seyfarth et al. 1980b), do sometimes respond with inappropriate escape behaviour.
To an extent, sure.
To an extent, Paul agrees.
To an extent they can.
It does to an extent.
"To an extent they have".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com