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For focal therapies, it is imperative not only to accurately differentiate significant from indolent prostate cancer [6, 7], but also to precisely identify the tumor borders.
Further studies with larger samples to increase the statistical power to differentiate significant differences among study phases should be considered.
It may be that treatment with ezetimibe for 2 years is insufficient to differentiate significant incremental clinical benefit, against a background of lipid-modifying and pleiotropic effects of statin therapy.
In contrast, our two methods, differential coexpression profile (DCp) and differential coexpression enrichment (DCe), are designed based on the exact coexpression changes of gene pairs, and thus can differentiate significant coexpression changes from relatively trivial ones, and identify coexpression reversal between positive and negative (Yu,H. et al., submitted for publication).
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As for chronic liver disease due to less common etiologies, ARFI proved reliable in differentiating significant from non-significant steatosis in children with biliary atresia [59] and in adult patients with autoimmune hepatitis [60] and with primary biliary cirrhosis [61].
Trigger value for the screening tests to differentiate between "significant" and "not significant" effects (Fig. 1, step 1).
Unlike our study, these studies did not differentiate between significant and non-significant proteinuria.
Some unsupervised procedures promptly give as output a map of the change that must then be interpreted assigning a threshold, in order to differentiate the significant change from the pixels which are unchanged.
Results displayed in Table 4 do not differentiate statistically significant from results displayed in Table 3.
Lastly, a small sample size of this study might contribute to an inadequate power to differentiate the significant difference in clinical efficacy among groups (if any).
To differentiate a significant bacteraemia from a contamination, the following criteria were proposed: type of bacteria, aerobes or anaerobes and growth rate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com