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It is able to differentiate cells devoted to nitrogen fixation (heterocysts, Figure 1C D), motile small celled hormogonia, used in the unique vertical transmission process, and resting akinetes (Figure 1E).
We developed a protocol that mimics mammalian liver development, to differentiate cells with pluripotent characteristics to hepatocyte-like cells.
To differentiate cells towards adipocytes, we treated spheroids from both adherent and sphere cells for 3 days with DMSO.
However, successful use of ESCs for clinical application requires the development of efficient methods to differentiate cells into specific lineages in vitro and reconstituting tissue function in vivo.
The most interesting observation is that in hESCs that have started to spontaneously differentiate (cells are growing bigger) have really high amount of Ncl/Oct4 complexes (Figure 3E), implying that the interaction may be important during initial differentiaiton.
Growth phenotypes allow microbiologists to describe and thereby differentiate cells.
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The analysis illustrates a unique capability of using ICA to differentiate cell performance and material utilization in different cell designs.
We applied this newly developed method to cell-based research to differentiate cell lines, cells at different cell cycle stages, and live/dead cells.
First, cMap does not differentiate cell lines in its prediction.
Furthermore, using differentiation and evaluation of failed-to-differentiate cells, the Pten−/− differentiated ESC samples paradoxically contain fewer tumor-initiating SSEA1/c-kit double positive ECCs relative to wild type cells in vitro.
To test the effects of glutamate in oligodendrocyte differentiation, we stimulated rapidly differentiating cells.
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