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Leydig cells, stromal elements, and supporting cells (primordia of Sertoli cells) differentiate around primordial germ cells early in gonadogenesis; testosterone secretion follows.
The retailers who will make it big in the next 10 years will be those who innovate and differentiate around people rather than channels.
The success of iPhone 4 has been astonishing to witness, despite the antenna issues, proving once again that Apple has a unparalleled ability to differentiate around design and integration, not simply "features".
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In terms of VHL's role during pancreatic development, we demonstrated that deletion of Vhl in endocrine α-cells and β-cells which terminally differentiated around E12.5 [40], does not appear to affect normal functions of endocrine pancreas during embryogenesis, postnatal development, and in adulthood (Glu-Cre;Vhl f/f and Rip-Cre;Vhl f/f animals).
The present study contributes supporting evidence in that FLAG-RARγ-expressing GFRα1+ cells preferentially differentiated around these stages (supplementary material Fig. S4D).
For the other items, differences in the relative contribution to the information between the two cutoffs were also small, which means that for differentiating respondents around the higher cutoff (X+ = 12), the relative importance of the items is the same as for differentiating around the lower cutoff (X+ = 9).
Primary myofibres begin to differentiate at around 35 days gestation, followed by secondary and tertiary fibres and by the first days of postnatal life this process is permanently inhibited [ 22].
Marvel and Sony are looking for a younger Spider-Man this time around, to differentiate the new take from previous iterations: both Maguire and Garfield were in their late 20s when they took the role.
Schlesinger et al. differentiate between target scenarios (around 460 TWh by 2050) and trend-based scenarios (560 TWh) for future German electricity demand [43].
The work follows on from an earlier Cell paper that showed the existence of an 'equilibrium signal' from differentiating blood cells centered around PVR.
And that difference isn't necessarily about you as an individual, it's much more simply about trying to augment and to differentiate what's around you.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com