Therefore, different tumours with distinct aetiologies should be differentially segregated in terms of their treatment regimens and especially their clinical trial assignments.
Interestingly, these markers were assessed in the mRNA expression data produced by Taylor et al (2010) and ANPEP and TRIP13 found to be significantly differentially expressed in terms of Gleason score and biochemical and metastatic recurrence, respectively (Supplementary Data Table 4).
By exploiting the network information from big data, recent studies on EdgeMarker [14,20] demonstrate that non-differentially expressed genes, which are usually ignored by traditional methods, can be as informative as differentially expressed genes in terms of classifying different biological conditions or phenotypes of samples.
IPA was used to interpret the differentially expressed proteins in terms of an interaction network and predominant canonical pathways.
In that study, all the patients investigated had functional impairment irrespective of psychopathology but those with psychiatric morbidity were differentially more impaired in terms of severity.
Figure 3 depicts the distribution of predicted functions of all the differentially expressed genes in terms of biological processes, molecular function, and cellular components.
This view is very intuitive to identify modules of correlated and differentially expressed genes in terms of well defined colored spots.
A total of 1500 genes (approximately 20% of all S. erythraea genes) were identified to be differentially expressed (DE) in terms of between-time series, which emphasizes on the expression variation at the same time point between two strains.
Specifically, we assessed the effects of these two chronic viral infections, alone and in combination, on the PBMCs using a comparative proteomic analysis in an attempt to identify differentially expressed proteins in terms of the mechanisms underlying HIV-1 and HCV mono- and co-infection.
A secondary aim was to evaluate whether patients showing different clinical signs of lumbar instability differentially benefit from LBs in terms of lumbar proprioception.
