Sentence examples for differential target from inspiring English sources
As Figure 1 demonstrates, no single gene within the pathway appears to be the differential target of CNA across the 18 breast cancer samples shown.or when examined across the remaining 127 individuals in the study.
Another interesting observation is that all of the identified target genes are regulated specifically by either the EWS/WT1 −KTS) or the (+KTS), but not both, clearly demonstrating the differential target gene specificity of the two isoforms.
For example, the precise mechanism behind the differential target site recognition of different A3 proteins on DNA substrates and the identity of specific RNAs that bind to A3 proteins remain poorly understood.
The native WT1 ±KTS) isoforms do not regulate any of these transcripts, indicating that the loss of zinc finger 1 and/or the presence of EWS transactivation domain (NTD) may confer differential target gene specificity to EWS/WT1.
To assess the potential roles of REST and CoREST in the modulation of glial gene expression programs, we also correlated changing profiles of REST and CoREST promoter occupancy with differential target gene expression patterns in cell types associated with critical developmental transitions.
An overview of the data indicates that PU.1, GATA1, and GATA2 achieve differential target gene expression through different mechanisms.
Because apical and basolateral membranes are only found in differentiated epithelial cells, genes critical for differential targeting may be specifically up-regulated upon MDCK cell differentiation.
Three of the miRNAs exhibiting differential targeting were themselves significantly differentially expressed; as expected, target sets had reciprocal expression to their cognate miRNAs.
Detailed attack analyses of cars from the US market could help resolve the exact role of handling costs in the differential targeting of some cars.
It is currently debated whether glucose facilitation of cognitive performance is due to differential targeting of hippocampal memory or whether task effort is a more important determinant.
To illustrate differential targeting of the FPs into specified cellular compartments, we studied and validated the expected subcellular localization of various C. guilliermondii predicted proteins fused to FPs.
