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Nevertheless, the potential clinical significance of the CR concept was revealed by the cautiously implemented, pre-specified, secondary assessment of a differential subgroup of CH patients with endoscopic healing who did not fulfil the CR criteria.
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The exploratory subgroup analyses showed consistency between the overall effect and the differential subgroup effect with a similar pattern of relationship between disability and participation limitation, strength, work status, and pain limited range of motion (Table 5).
The subgroup analyses of the primary outcome based on men and women showed consistency between the overall effect and the differential subgroup effect with a similar pattern of relationship between the WORC and independent factors in majority of the cases except for age, having a repair, medication use, and expectations for improved ADL and ROM (Table 5).
Also, differential existed across subgroup of women in the two regions.
Specifically, for some of those oligonucleotide probes several brain samples displayed significantly stronger HML-2 signal intensities in microarray experiments than other samples, suggesting differential expression of (a subgroup of) HML-2 loci.
The rapid response and the sensitivity shown by the differential expression of this subgroup of miRNAs to the partial disappearance of K-Ras in the 6-day 4OHT-treated MEFs suggests the potential significance of their differential expression in relation to the initial steps of generation of the Rasless phenotype.
Inconsistent findings may rely on varying educational effects of various programs and differential effects on subgroups of patients.
Manual therapy had no differential effect on subgroups of patients defined by baseline pain or hip function.
However, relatively few studies have investigated the differential pathogenesis in subgroups of FD according to the Rome III definition.
In addition, some of the inconsistencies in this area of research might be due to differential sampling of subgroups of lead-exposed children characterized by different levels of psychosocial adversity.
These inconsistencies may rely on varying educational effects of various methods and contents, as well as on differential effects on subgroups of patients.
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