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These observations indicated that the abundance ratio based on peptide spectral counts cannot be simply used as indicators for differential significance between diabetic and non-diabetic serum.
According to our pathway-associated differential significance analysis, we found keratin associated pathway were significantly overall bias with diabetic serum, which might not result from the bias of sample preparation.
Six differential significance subnetworks were finally identified for the six brain regions, respectively.
Ten papers examined the relationship between adherence and the clinician-patient alliance, which emerged as a consistent predictor, though its components have differential significance.
These distinct pathogens possess different risk factors, or select risk factors for resistance may carry differential significance for the varying organisms.
This study provides provocative evidence suggesting a possible differential significance of t-PA and u-PA expression in human breast cancer.
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Breitling et al. proposed a simple method named GiGA which receives a list of genes ordered by their differential expression significance and extracts subnetworks corresponding to the most differentially expressed genes [31].
A total of 23,195 microarray probes passed the differential expression significance threshold (see Methods).
Differential expression significance was calculated using rank expectation, at multiple-testing-adjusted P value of P≤0.01 (Thomas et al., 2011).
The user can also filter the results by non-differential or differential enrichment significance, the size of the enriched region or enrichment in the control dataset.
First, we computed the differential expression significance of each gene (R) in the prostate cancer gene expression data using the Student's t-test.
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