Exact(51)
The differential reactivity is exploited to introduce two orthogonal reactive handles onto the surface of a double cysteine mutant of superfolder green fluorescent protein in a regioselective manner.
This differential reactivity might be a consequence of a particular and differentiated exposure of each one of the antigens to the host immune system due to their specific location in the parasite [ 27, 34] or, alternatively, to the ability of the immune system to recognize antigens depending on the stage of the illness.
Kufe, D. et al. Differential reactivity of a novel monoclonal antibody (DF3) with human malignant versus benign breast tumors.
These unusual congeners of the more common Mo and W analogs may offer new catalysts for the olefin metathesis with differential reactivity and selectivity.
A 1,4-hydroboration reaction was exploited for the thermal generation of regio-defined enol boranes, and a unique electron-deficient ligand was found to exhibit differential reactivity in the subsequent alkylation reaction.
An independent confirmation of this differential reactivity was obtained from density functional theory (DFT) calculations using 1,2,4-triazole nucleoside as an example.
Similar(9)
17 In view of the constrained conformation of the peptide ligand in the MHC groove, we investigated (by HPLC analysis) whether the loaded ligands p*AA syn or p*AA syn / anti would show differential reactivities towards periodate.
This is in accord with the differential reactivities in these two bands under different experimental conditions, including a more pronounced response to treatment with levodopa in the beta 1 than beta 2 range (López-Azcárate et al., 2010; Marceglia et al., 2006, 2007; Priori et al., 2004).
However, our data also demonstrate that tumour cells and endothelial cells can be distinguished by their expression of HPA1; the high levels of this enzyme on tumour cells compared to its weak expression on the endothelium is likely to contribute to the differential reactivities of the HS found on the surfaces of these two cell populations.
In addition to the phase shift in gene cycling between control and irradiated seedlings over time, the oscillation of a subset of transcripts might also indicate differential cell reactivity to IR within seedlings (e.g., dividing vs differentiating, cotyledon vs root) and/or differential transcript stability after IR.
During pubertal development, the brain and HPA axis undergo extensive maturational processing, characterized by altered HPA axis reactivity, increased synaptic connections, and differential responsiveness to the effects of gonadal steroid hormones [5], [6], [7], [8], [9].
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