Sentence examples for differential predisposition from inspiring English sources

Therefore, identification of such variation is a major step toward understanding the differential predisposition to common diseases and variation in drug responses among individuals and ethnic populations.

Since the variants were generally common in current populations, they will likely prove useful for validating expression differences across multiple tissues, populations and enhancing our understanding of the differential predisposition to common diseases and variation in drug responses in different ethnic groups.

Recently, we found that genetic variants at the miR-124 binding miR-124 bindingositeeton-organizing IQGAP1 gene confer differenthel predisposition to breast cancer [47].

33 While some subjects thrive and some break down under similar adverse circumstances due to neuroendocrine stress-related psychopathology, differential genetic predisposition to neuroendocrine stress response is expected.

In addition to ancestry, Dr. Francke noted that researchers are beginning to find genes associated with differential drug response and predisposition to disease.

It is likely that many of the important moderating effects of the environment associated with alcohol use and related externalizing behavior reflect differences in social control and/or opportunity, resulting in differential expression of individual predispositions (Shanahan and Hofer 2005).

The expectation is that this response is not uniform in all patients but, rather, is modulated by either preoperative genetic predisposition or postprocedure differential regulation of the innate immune response to injury that promotes a maladaptive phenotype leading to intervention failure.

In fact, a polymorphism described in that chromosome X copy was found associated with MS predisposition and with differential expression of MSRV [26].

A large body of evidence supports the association between stress, clinically significant depression, and activation of the immune and neuroendocrine systems (Woiciechowsky et al. 1999; Berk et al. 2011; Gibney and Drexhage 2013), although it still remains unclear if differential reactivity to stress reflects a predisposition or a marker of illness activity or both.

We wished to see whether the association that we had found between the CD154 microsatellite and predisposition to RA was sustained by the differential expression of the gene variant associated with RA.

In the 1960s, the 'thrifty genotype' hypothesis suggested that populations varied genetically in their predisposition to store energy, on account of differential ancestral exposure to 'cycles of feast and famine' (Neel, 1962).