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Additionally, the simulations allowed us to focus exclusively on the role of epistasis, where in the experiments there remains the possibility that population divergence resulted, at least partially, from differential niche specialization.
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However, randomization tests, which estimated the effects of differential habitat availability on niche breadth for native and introduced populations, were unable to reject the hypothesis that the observed niche expansion resulted solely from differences in available habitat between native and introduced ranges.
Molecular variability might account for differential susceptibility to the obesogenic niche, but the niche itself is a prerequisite for obesity except in the case of very rare genetic disorders (O'Rahilly et al., 2003).
Endophyte-symbiotic P. leptocoma seeds germinated with greater frequency in P. leptocoma niches relative to P. reflexa niches, whereas neither endophyte-free (experimentally removed) P. leptocoma seeds nor P. reflexa seeds showed differential germination between the two niche types.
The transport and secretion functionality associated with HVRs 1 and 4 is consistent with the assertion of Coleman [ 19] that these islands may play a role in niche adaptation by supporting differential nutrient acquisition capabilities.
The presence of parallelisms in phenotypic adaptation of Lake Baikal and other whitefishes toward the use of the pelagic niche accompanied by parallelism in differential pattern of expression is discussed.
In particular, it is increasingly assumed that subtle differences in the type and magnitude of the host-pathogen response at the level of the vaginal mucosa may explain the differential susceptibility to perturbation of the vaginal niche [ 23].
These concerted changes present an opportunity to study differential gene expression of SSC and their niche by cross-comparison of purified Spga and Sertoli cells at two crucial stages of testis development.
There are however genes belonging to signaling pathways such as Ephrin and Shh whose differential expression is confined to the prostate stem cell niche (Table 4).
Is the presence of parallelism in phenotypic adaptation of Lake Baikal and other whitefishes toward the use of the pelagic niche accompanied by any parallelism in the differential pattern of expression?
These results provide the validity to the newly developed hypoxia/reoxygenation culture system for examining the regulation of CSCs in breast cancer cell lines by niche factors in the tumor microenvironment and developing differential targeting strategies to eradicate breast CSCs.
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