Differential localization patterns of Zn II Pz derivatives between cell types did not appear to influence the overall PDT effect.
Future work should seek to establish whether these differential localization patterns are modulated by depletion of individual Exocyst components.
We show that all Exocyst components are required for cytokinesis in mammalian cells, but that these proteins exhibit differential localization patterns; Sec5 and Exo84 populate the growing furrow during early telophase, whereas other exocyst components do not.
To address this issue, we compared Numb half-life in SCB29 and SCIET27 cells, in which Numb display a differential subcellular localization pattern.
Here we further show that CTCs present a differential TWIST subcellular localization pattern.
Although Stp1 and Stp2 have redundant functions, recent research provides evidence that they have functionally diverged as can be inferred from their differential regulation and localization pattern (Wielemans et al., 2010; Tumusiime et al., 2011).
In fact, various protein kinase splice variants have been experimentally characterized and they are shown to elicit different expression patterns, differential localization and hence different functional properties [ 23- 26].
Surprisingly, we found no vulval morphogenesis defect in lin-12 wy750) lin-12 wy750er by differential interference contrast (DIC) mutantsopy or theitherlization pattern of the ajm-1::gfp apical junction marker at several development stages (Koppen et al., 2001).
