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Arbes [8] has developed differential line protection scheme for the protection of double lines, tapped lines and short lines.
A close inspection shows differential line broadening, which reveals the different dynamic interactions between SH3 and SH2 with the kinase domain.
13C-Methyl-transverse relaxation optimized spectroscopy measurements of the PIDDosome core exhibit signs of differential line broadening, cross-peak splitting and chemical shift heterogeneity that reflect the presence of non-equivalent sites at interfaces within an asymmetric complex.
Similar(57)
Blast disease scores measured on 18 differential lines in Andranomanelatra in 2011 and 2015.
However, the blast disease scores measured in 2011 and 2015 on 18 differential lines (i.e. carrying different resistance genes) both in Andranomanelatra were very similar.
Under our natural infestation conditions, the genetic structure of M. oryzae populations was complex, with a broad virulence spectrum as observed in our panel of differential lines.
As with the P119L variant, the differential line-broadening induced by the double mutation of FKBP52 does not propagate from the β4 β5 loop into the β3a strand as it does for FKBP51.
Once again, the pattern of differential line-broadening along the residues of the β4 β5 loop was quite similar to that for the P119L variant of FKBP52 and to that for FKBP51, suggesting that a similar conformational transition is being monitored.
The following previously published datasets were used: Marchetto MC, Narvaiza I, Denli AM, Benner C, Gage FH, 2013, Differential LINE-1 retrotransposition in induced pluripotent stem cells between humans and great apes, http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi acc=GSE47626, Publicly available at the NCBI Gene Expression Omnibus (Accession no: GSE47626).
We observed that the differential line-broadening within the β4 β5 loop increased 3-fold for the P119L/P124S double mutant of FKBP52, relative to the P119L variant, yielding a line-broadening effect that was 60% of that observed for FKBP51 (Supplementary Figure S3).
Tests of allelism were performed in this study by intercrossing 'Cantala' with barley differential lines carrying Rph3, Rph7, Rph10, Rph12 and Rph13.
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