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Detailed patient information such as age, gender, histological type, differential grade, pathologic stage and history of using alcohol/smoking is listed in Table S5.
T-stage, N-stage, overall stage, differential grade, ER status, PR status, Her2neu status and CTC were significant for RFS and BRD.
This shows that T-stage and differential grade are independent prognostic factors for recurrence, but that preoperative presence of CTC is not (P = 0.155).
Certainly, it is the differential grade in the outcome that justifies the need to identify biomarkers that can predict the clinical benefit of sunitinib.
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However, these results do not take into account the differential grading practices across courses that blacks and whites take.
The working electrodes were polished with differential grades of silicon carbide paper, rinsed with distilled water and dried with acetone.
Based on the extent of the differential methylation grade, the importance of the biological functions, the design of suitable primers and the availability of antibodies, we decided to validate DIO3 and FOXD2 by methylation-specific PCR (MSP) and pyrosequencing, respectively, and by quantitative polymerase chain reaction (qPCR) and immunohistochemistry (IHC) for both.
Traditionally the differential diagnosis, grading and staging of prostate carcinoma has been based predominantly on morphological features [ 9, 22, 23].
Genes that showed consistent differential expression between grade 2 and 1 tumors and grade 3 and 1 tumors were assessed for their prognostic ability.
Using SAM, the authors found 28 genes differentially expressed between grades I and II meningiomas, and no differential expression between grades II and III.
High grade differential GPS units were used to locate the plots.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com