In order to achieve this, we designed a robust internal structure encompassing specific pre-defined modules (which can be found under the "Filters" section in the database) including " pancreatic specimen/cell type", " pancreatic differential expression information", " genes differentially expressed in" and " genes expressed in" modules.
Custom gene expression measurements, differential expression information, and gene-to-group mappings can be uploaded and can be used for further filtering.
Putative functional characterizations of modules regarding F. graminearum-resistance and QTL activity were derived by integration of differential expression information, GO enrichments, and the corresponding module eigengene.
Its web interface enables a straightforward retrieval of known differential expression information on a query gene and a comparison of signatures to prioritize common genes.
The main reason why biclustering methods do not use differential expression information is that they do not specifically focus on the analysis of perturbational data.
Upon searching for those genes on Liverome, differential expression information of eight of the genes (CSF1R, CTNNB1, CDKN2A, RB1, HNF1A, KRAS, MET, and PTEN) was retrieved (Table S4, Additional File 1), which may provide further understanding of these genes.
Differential gene expression information specific for the class of compound under study may be employed to optimize prioritization of compounds within that class for further testing.
The EST data obtained and submitted to the GenBank database as well as the transcriptional profiling from the microarray study provide sequence and differential gene expression information for hepatic genes in the pig.
Differential gene expression information from the Illumina 1 G sequencer was obtained by aligning reads to a reference genome and counting the number of reads that overlap each ORF.
For determination of differential expression, probe set information is summarized into gene level information, and the analytical methodologies remain unchanged from those used for 3' IVT array data.
Such modifications will lead to differential expression of similar information depending on the surrounding conditions, resulting in gene activation or silencing.
