Because, these differential cell divisions probably resemble those extensively characterized during peripheral nervous system development, we initially focused on using this new information to generate glands containing reduced numbers of secretory cells, without disturbing the epithelial portion of the gland.
After the flowers open, unequal growth continues from stage A1 until the mature flower stage A2 and establishes the major size differences between the two petal pairs, likely via differential cell division, as described by [ 10].
The second hypothesis is strongly supported by developmental studies in planarians (Takeda et al. 2009; Watanabe K, unpublished data) indicating that the two-celled prototypic eyes of Polycelis auricularia (fig. 1) arise by differential cell division from a common precursor cell.
Using the fate mapping approach, we show a difference in cortical numbers in specific laminae between dorsomedial and adjoining ventrolateral cortex at the level of both somatosensory and visual cortices indicating that differential IPC division between adjoining areas might lead to areal differences in the mature cortex.
Regional differentials (administrative division) on childhood morbidity in Bangladesh were also observed in previously published studies.
In many tissues orientation of cell division is coupled to the regulation of differentiation producing daughters with similar (symmetric cell division, SCD) or differential fate (asymmetric cell division, ACD).
We tested for, and excluded a potential mechanism based on differential T cell division in the cervical versus mesenteric nodes, using the dye CFSE to stain T cells and dilution of the dye to indicate cell proliferation.
These ISCs reside within an epithelial monolayer, and upon cell division, differential levels in Delta/Notch signaling between daughter cells result in the production of an undifferentiated enteroblast (EB), which directly differentiates into a large epithelial-like enterocyte (EC) or a hormone-secreting enteroendocrine (ee) cell (Micchelli and Perrimon, 2006; Ohlstein and Spradling, 2006, 2007).
We suggest that this may be a general mechanism for maintaining tissue integrity during cell division and differentiation during differential growth.
Recently, we described a new categorization of HPV infections based on serial measurements of type-specific viral load, and proposed an underlying mechanism based on differential cervical basal cell division after infection (Fig. 1).
