Therefore, unlike the classical diffusion assay which reports on the absolute antimicrobial effect of a compound, the assay we developed is sensitive to the differential effect of compounds on competing microbial strains.
We used the differential cytotoxicity of compounds across cell types and species to construct profiles of cell lines according to the compounds that were toxic to them and profiles of compounds according to the cell lines in which they were toxic.
Differential effects of compounds on in vitro organic acid and base trasport provides information about the transport of these compounds as well as about their nephrotoxicity.
In summary, we developed a sensitive differential assay for compounds that select against antibiotic resistance.
Building on this well-established technique, we developed a competition-based method for detecting the differential impact of compounds on the selective advantage of resistance.
Alternatively, if differential synthesis of compounds is not the cause of day-night differences, then differential transport to the cuticle or differential loss from the cuticle must be invoked to explain day-night changes.
These structural data reflected the findings from the in vitro assays and helped explain the compounds' differential activity on ERα and ERβ.
The lack of smartphone adoption caused by the price differential is actually compounded by the lack of a resale market in the region.
The lack of smartphone adoption caused by the price differential is actually compounded by the lack of a resale market in the region.
