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Potential inconsistency among different types of trial (designs) differing in the set of treatments tested is a major challenge, and application of procedures for detecting and locating inconsistency in trial networks is a key step in the conduct of such analyses.
The order in which the different types of trial run were completed was counterbalanced across observers (Simultaneous-Sequential-Simultaneous-Sequential, or Sequential-Simultaneous-Sequential-Simultaneous).
The different types of trial were presented in a quasi-random order.
Medians and ranges were calculated overall for the different types of trial and then broken down by endpoint and whether the trial was public or industry funded.
Different types of trial design, such as placebo control and multi arm, anxieties about side effects or the extra effort that some trials require may all be disincentives.
Similar(55)
Even when combining split-mouth and parallel-arm RCTs in the same meta-analysis, consideration should be given to potential differences between the different types of trials in subgroup analyses, until there is more evidence that the two designs do not systematically differ.
However, it is important to point out that such conclusions are based on the observation of the averages, once we did not run tests within participants to compare their performance regarding the different types of trials, that being one of the limitations of our study.
or modeling the RT effect separately for different types of trials did not affect the results.
Reviewer #2: First, the author claims that different types of trials result in differential neuronal activity in the hippocampus.
First, the author claims that different types of trials result in differential neuronal activity in the hippocampus.
In each task, different types of trials occurred in pseudo-randomized order with the constraint that the type changed between consecutive trials.
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CEO of Professional Science Editing for Scientists @ prosciediting.com