In line with this finding, stratification for different types of mutations and mutational subgroups generally revealed slightly increased HRs (for details see Table 3).
First, the time of amino acid substitutions in Gag was analyzed cumulatively by type of mutation irrespective of the individual contribution by each subject, providing an overall summary of the time and timing differences between different types of mutations.
And finally, do differences in morphology and differences in behavior arise through different types of mutations?
We absolutely agree that different types of mutations would accumulate differently, and have expanded the text to describe this issue and justify our modeling of a particular class of mutation those that directly affect intracellular replication rates.
This difference is due to the effects of different types of mutations on MeCP2 function.
Cell lines were chosen that carry different types of mutations in NIPBL with predicted differing effects on the resulting protein.
We prefer the word "mutate" to "alter" because the different types of mutations in genetics generate constructive ideas on how an experiment can be redesigned.
Next, we were interested what the improvements were for different types of mutations based on the secondary structure and accessible surface area of the mutated residue.
Different types of mutations and point mutation rates that depend on codon base number are considered in this study.
The elucidation of the DNA structure provided the essential foundation for defining the different types of mutations arising from both spontaneous and environmental DNA damage that affect all living cells12.
To characterize specificity, we formulated a model system with several MBs of highly similar sequence, but different lengths, and template RNAs carrying different types of mutations.
